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Water Soluble Solubilizing Agent Vitamin E TPGS Non Ionic Surfactant

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Water Soluble Solubilizing Agent Vitamin E TPGS Non Ionic Surfactant

China Water Soluble Solubilizing Agent Vitamin E TPGS Non Ionic Surfactant supplier

Large Image :  Water Soluble Solubilizing Agent Vitamin E TPGS Non Ionic Surfactant

Product Details:

Place of Origin: China
Brand Name: Jason
Certification: Kosher, ISO9001:2008

Payment & Shipping Terms:

Minimum Order Quantity: 25kgs
Price: USD175-190/kg
Packaging Details: 25kgs/drum
Supply Ability: 5tons/month
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Detailed Product Description
CAS No.: 9002-96-4 Appearance: White To Brownish Waxy Solid
Purity By HPLC: Not Less Than 99.5% Odor: Nearly Odorless

PRODUCT NAME: Water Soluble Vitamin E

CAS #:9002-96-4

 

Vitamin E TPGS (d-α-tocopheryl polyethylene glycol 1000 succinate) is a water-soluble derivative of the natural form of vitamin E, d-α-tocopherol. It is produced by the esterification of crystalline d-α-tocopheryl succinate by polyethylene glycol 1000. It is a multirole excipient for pharmaceutical drug delivery innovation. Vitamin E TPGS is a non-ionic surfactant used as:

  • solubilizer of poorly soluble drugs
  • absorption enhancer
  • emulsifier
  • vehicle for lipid-based drug formulation
  • antioxidant

Vitamin E TPGS is also used as an efficient source of natural Vitamin E both for therapeutic and nutrition purposes.​



Vitamin E TPGS in drug formulation​

Formulation fields:
Vitamin E TPGS has been used mainly in oral dosage forms for years but new delivery applications are being investigated in parenteral, nasal, ophthalmic, dermal deliveries​​

 

Benefits:​
- Enhancement of Bioavailability by increasing solubility of poorly water-soluble APIs and by formulation of Self Emulsifying Drug Delivery System (SEEDS)​
- Thermal stability for hot melt extrusion as a versatile plasticizer with solubilizer properties and as Antioxidant for sensitive excipients​​​

 

Specification:

Item Specification
Appearance white to brownish waxy solid
Purity by HPLC Not less than 99.5%
Odor Nearly odorless
Acidity[mg KOH/g] Not more than 1.5
Content of VE Not less than 250mg/g
Solubility in water 20g sample can be dissolved in 80ml boiling water

 

helf life :2 years

Country of origin : China

 

Standard : In house standard

Package size :20kgs/drum

Storage : Keep tightly closed in a dry place. Do not expose to excessive heat or cold

Contact Details
Wuhan Jetide Biotech Co.,Ltd.

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